Mrsa | Survey Shows Vancomycin Continues To Dominate MRSA Treatment

According to surveyed infectious disease specialists and internists as well as hospital patient-level medical data, Decision Resources and Arlington Medical Resources (AMR) find that vancomycin”which has experienced increasing usage over the past five years”continues to dominate treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. Sixty to 76 percent of surveyed infectious disease specialists indicate that they use vancomycin as first-line treatment for bloodstream infections (BSIs), complicated skin and skin structure infections (cSSSIs) and hospital-acquired pneumonia (HAP) suspected to be or confirmed to involve MRSA.

Pfizer’s Zyvox (linezolid) and Cubist’s Cubicin (daptomycin) have been on the market for years and have steadily gained patient share and days of therapy with Zyvox having made notable gains in the treatment of HAP and Cubicin having gained usage for the treatment of bacteremia. However, despite increased usage, comparable efficacy to vancomycin in various indications and delivery advantages over vancomycin, neither Zyvox nor Cubicin have been able to supplant vancomycin as the preferred MRSA therapy in the hospital setting.

Study findings also reveal that surveyed infectious disease specialists consider sepsis and prosthetic joint infections to be the top most difficult-to-treat indications needing novel anti-MRSA therapies. Notably, 42 percent of surveyed infectious diseases specialists consider sepsis a top priority for novel agents to treat MRSA and 29 percent of surveyed internists agree. Additionally, patient level audit data of drug costs and usage reveal high antibiotic costs for sepsis and prosthetic joint infections owing to long treatment duration and use of premium-priced antibiotics.

“Sepsis is an indication for which there is little drug development and few treatment options and although drug development for this indication is a high risk, as

Click here to view rest of article from original site

Mrsa Kids Light T-shirt  by Cafepress Mrsa Kids Light T-shirt  by Cafepress

“mrsa” Plush Toy  by Giant Microbes

Facebook Twitter Email