Mrsa | UK Biotech Company Leading Fight To Cure E. Coli


UK Biotech Company Leading Fight to Cure E. coli

CAMBRIDGE, England , July 6, 2011 /PRNewswire/ —

A Cambridge -based biotech company is leading the fight againstpotentially fatal bacteria such as MRSA and E. coli ,attracting new funding to develop its pioneering treatment whichcould play a vital role in treating outbreaks such as those in France and Germany .

Phico Therapeutics has recently raised 1 million of furtherfunding to develop a range of medical products based on its novelantibiotic technology,SASPject[TM], which is provingeffective in targeting bacteria resistant to conventionalantibiotics.

SASPject[TM] PT3.X deactivates bacteria and prevents the releaseof toxins, halting the infection in its tracks. Unlike conventionalantibiotics, SASPject only affects the targeted bacteria, leaving’good’ bacteria unharmed.


SASPject[TM] PT3.X deactivates bacteria and prevents the releaseof toxins, halting the infection in its tracks. Unlike conventionalantibiotics, SASPject only affects the targeted bacteria, leaving‘good’ bacteria unharmed.

Dr Heather Fairhead is Chief Executive of Phico Therapeuticswhich employs 19 staff at the Babraham Research Campus near Cambridge :

“There is currently no effective antibiotic treatment for thisgroup of severe food-poisoning types of E. coli, and we arenow witnessing the tragic human and economic consequences of thisinfection in Europe . It is vital that we continue to trial andrefine these new products and this latest round of funding isextremely welcome,” she said.

The active agent in SASPject is an antibiotic protein calledSASP. It works by binding to bacterial DNA and deactivating it -–switching off all primary functions in the bacterial cell andstopping it from reproducing. Crucially, SASP can bind to any pointon the DNA, making it virtually impossible for bacteria to developresistance to it.

A type of virus known to target only bacteria is used to carrythe SASP gene


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