Staph Infection | Merck Ends Staph Infection Vaccine Study, Calls Drug A Failure


NEW YORK- Merck Co. and Intercell AG said today they have ended a trial of a potential vaccine for Staph infections because the vaccine was not working, and because patients who took the vaccine were more likely to die.

The companies said a data monitoring committee unanimously recommended that they cancel the study of V710, which is designed to prevent Staphylococcus aureus infections .

Merck and Intercell said the data showed the vaccine was “unlikely to demonstrate a statistically significant clinical benefit.” They also said patients who were treated with V710 were more likely to have multiple organ failure and die.



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They said a review of the data showed the increased risk of death was not statistically significant.

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